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There is no cure of FH but early identification of children with familial hypercholesterolemia is essential to provide early treatment and prevent long-term problems. Treatment begins with dietary changes that include eating a healthy diet that is low in total fat and minimizes intake of saturated fat. Individuals should also eat foods with high fiber content and a wide array and adequate servings of fruit and vegetables. Diet changes can decrease cholesterol levels by as much as 10 percent.
Individuals should maintain an active lifestyle; ideally, exercising on most days for at least 30 minutes is recommended. If diet and exercise changes are not sufficient to lower cholesterol, a variety of cholesterol lowering drugs can be started.
Once children have been tested for familial hypercholesterolemia with a fasting lipid panel, they should be referred to a lipid specialist who can monitor lipid levels, ensure that diet changes have been implemented, and decide whether a cholesterol-lowering drug is needed.
-Anthony F. Porto, M.D., M.P.H., director, pediatric gastroenterology, Greenwich Hospital in Greenwich, CT; and assistant professor of pediatrics, Yale Medical Group
